IMLYGIC® (talimogene laherparepvec; T-VEC) ACTION PLAN

The content in this action plan is intended to aid you in educating your patient with melanoma about how to take Imlygic. In addition, the customizable content provides key written information on safety aspects and adverse-event management. Below is a brief description of the different pages available to you and how to use them. Whether you print this whole action plan or just certain pages, we trust that you will find this resource from the MNI a helpful companion to our healthcare provider materials.

Pages/Sections

You can choose to print whichever pages/sections you would like. You also have the option of reading the annotations for each page before printing or just selecting the specific pages by title below, and downloading.

You can also download all of the pages as a multi-page pdf by clicking here.

ACTION PLAN COVER

This is a cover page for the oncology team member to fill out for the patient. It contains the patient’s name, the date, a list of the side effects discussed, and key points. It also contains Amgen resources on Imlygic. With this tool, you can create customized notes to guide your patients on their treatment journey.

Download The ACTION PLAN COVER PAGE

TAKING THE MEDICATION

This section provides specific recommendations for taking Imlygic, with a focus on preventing infectious complications or spread. It also reviews the more common side effects associated with Imlygic. It also explains that you may provide pages on specific side effects that you are concerned about—thus creating customized content for each patient.

Download The TAKING THE MEDICATION PAGE 1 of 3

Download The TAKING THE MEDICATION PAGE 2 of 3

Download The TAKING THE MEDICATION PAGE 3 of 3

NAUSEA/VOMITING

This page discussing nausea/vomiting is the first of the detailed pages on side effects associated with Imlygic. The Red Flags section describes symptoms that require immediate care from your office or the Emergency Department. The section Managing Your Side Effects provides specific self-management strategies patients can implement to alleviate nausea and vomiting at home.

Download The NAUSEA/VOMITING PAGE

FLU-LIKE SYMPTOMS, FEVER WITH OR WITHOUT CHILLS

This page discusses the flu-like symptoms that can occur with Imlygic. The Red Flags section describes symptoms that require immediate care from your office or the Emergency Department. The section Managing Your Side Effects provides specific self-management strategies patients can implement to prevent or alleviate flu-like symptoms.

Download The FLU-LIKE SYMPTOMS, FEVER WITH OR WITHOUT CHILLS PAGE

HERPES INFECTION

This page discusses the symptoms associated with herpes infection, which can occur with Imlygic. The Red Flags section describes symptoms that require immediate care from your office or the Emergency Department. The section Managing Your Side Effects provides specific infection-precaution strategies patients can implement to avoid contracting or spreading herpes infections.

Download The HERPES INFECTION PAGE

INJECTION SITE PAIN, SWELLING, OR INFECTION

This page discusses the symptoms associated with complications that can occur at the Imlygic injection site. The Red Flags section describes symptoms that require immediate care from your office or the Emergency Department, including cellulitis. The section Managing Your Side Effects provides specific self-management strategies patients can implement to relieve injection-site symptoms.

Download The INJECTION SITE PAIN, SWELLING, OR INFECTION PAGE

RESOURCES

This page provides specific phone and internet resources provided by Amgen for patients taking Imlygic. It also includes additional targeted therapy resources from AIM at Melanoma Foundation and the American Cancer Society.

Download The RESOURCES PAGE