Reply To: CNS Disease

[Anonymous]

HI Brianna,

From my experience I would proceed with additional imaging, to rule out increased edema, radiation necrosis, and/or additional disease. The usual culprit I see is increased edema, s/p radiation coinciding with the start of ICI’s. Alternatively, you could just restart some very low dose dex (i.e 1-2 mg BID) and see if his symptoms resolve spontaneously. If so, then a really slow taper would be in order.

Great question!
Lisa