if there is a 10% weight loss or gain a weight based dosing can be evaluated for and adjustment. However, if we have a combination or a flip dose situation ( ipi 1mg/kg & nivo 3mg/kg) we may adjust accordingly to a clinical situation of weight loss or gain. My institution and practitioners tend to stick with the weight based dosing though.
I am so excited to hear that you are considering taking back to your institution some of the updated dosing recommendations, please know that we continue to be here as a source of support for you, your colleagues & patients. Thank you again for your engagement & inquiries. Happy Healthy Thanksgiving!
All the Best,