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Does the patient appear unwell? Changes in weight since last visit Appear heavier? Thinner? Changes in hair texture/thickness? Appearing hot/cold? Does the patient look fatigued?
Read moreEnsure that patient undergoes thyroid function tests prior to first dose, every 12 weeks while on PD-1 therapy and q3 weeks with ipilimumab High TSH with low free T4 consistent with primary hypothyroidism DDX: secondary hypothyroidism due to hypophysitis, low TSH and low free T4 Occasionally thyroiditis with transient hyperthyroidism (low TSH and high free
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