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      Are any premedications given to prevent infusion reactions with ICIs?


        We do not routinely give premedication for ICI’s. If a patient develops an infusion reaction, they will receive premedication thereafter.


        Our approach is consistent with Virgina’s. I will add that there are some centers which have guidelines to premed before therapies, several years ago when ICI’s were launced, it was identified that some community based centers were pre-meding prior to infusions of ICI’s. An emphasis of education and understanding of the mechanism of action of these agents was and continues to be underscored.

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